AdSave up to 80% on your Sildenafil prescription. Use at your local pharmacy to save now! Get your mobile Sildenafil savings coupon instantly. No sign-up required & save instantly!Adults 65 years of age and older—25 mg as a single dose no more than once a day, 1 hour before sexual intercourse. The recommendation is not to exceed a dose of 25 mg of sildenafil in 48 hours if taking ritonavir. With intravenous use for Pulmonary arterial hypertension Manufacturer advises reduce dose to 10 mg twice daily with concurrent use of moderate inhibitors of CYP3A4. Small case studies in pregnant women with PAH indicate a low risk of harm, though caution is warranted. To provide you with the most relevant and helpful information, and understand which information is beneficial, we may combine your email and site usage information with other information we have about you. Do not use a kitchen teaspoon as it will not measure the right amount.AdSave on 50, Brand Name & Generic Drugs With SingleCare®. Get Your Free Rx Coupon Now! Save Up to 80% on Prescriptions at Over 35, Pharmacies Nationwide with a Free Rx Coupon/5 (2, reviews)Site visitors: Over K in the past month. The four main medicines taken by mouth for erectile dysfunction are: Avanafil (Stendra). Sildenafil (Viagra). Tadalafil (Cialis). Vardenafil. These medicines are called PDE5 inhibitors. They enhance the effects of a chemical the body makes that relaxes muscles in the penis, called nitric oxide. Sildenafil oral tablet is a prescription medication used to treat erectile dysfunction (ED) and pulmonary arterial hypertension (PAH). Typical dosage: 50 mg, taken as needed about 1 hour.This medicine usually begins to work for erectile dysfunction within 30 minutes after taking it. Advise patients to seek prompt medical care in the event of a sudden loss of hearing or decrease while taking sildenafil. Store mixed oral liquid in the refrigerator. Consider starting at a dose of 25 mg in patients with hepatic dysfunction e. You’ll soon start receiving the latest Mayo Clinic health information you requested in your inbox. You may opt-out of email communications at any time by clicking on the unsubscribe link in the e-mail. Contraindications Nitrates increase cGMP formation, while sildenafil inhibits cGMP degradation causing the combination to produce severe life-threatening hypotension synergistically; coadministration of sildenafil with nitrates is contraindicated.